Gut Health Test

Product Overview

Gut Health Test

Key Benefits

• Measures functional output – revealing how your gut bacteria and body work together to produce health-linked metabolites.
• Science-backed markers – analyzes three key tryptophan-related metabolites linked to gut, immune, and metabolic health.
• Advanced analysis – uses HPLC-UV-FLD technology for high-precision results.
• Balance insights – shows how a protective metabolite from gut bacteria relates to other insightful markers.
• Clear scoring – your results distilled into an easy-to-read Gut Health Index.
• Personalized guidance – tailored diet and lifestyle recommendations, with a focus on fiber and polyphenols, based on your unique results.
• Simple at-home self-test – dried blood spot (DBS) collection, no stool sample required.

What We Measure

This test focuses on three scientifically important compounds:

• Indole-3-propionic acid (IPA): A beneficial metabolite produced exclusively by gut bacteria from dietary tryptophan. Higher levels are linked to stronger gut barrier integrity and protection against oxidative stress. IPA is increasingly recognized as a key indicator of gut microbiota function and overall resilience.
• Tryptophan (TRP): An essential amino acid obtained from the diet that serves as the precursor for both IPA and kynurenine. Tryptophan availability and how it is metabolized can influence gut health, immune function, and metabolic balance.
• Kynurenine (KYN): A metabolite produced from tryptophan through the kynurenine pathway, often activated by increased immune stress. Higher kynurenine levels and an elevated KYN:TRP ratio are linked to immune activation and a shift away from beneficial microbial metabolite production.

We also calculate these key ratios:

• IPA:TRP ratio – Reflects the efficiency of your gut microbiome in converting dietary tryptophan into IPA.
• KYN:TRP ratio – Indicates immune stress and activation.
• IPA:KYN ratio – Represents the balance between protective and stress-driven pathways in tryptophan metabolism.

Your report also includes a Gut Health Index, integrating all markers and ratios into a clear overview of your gut-immune-metabolic balance.

Why Tryptophan Metabolism Matters

Tryptophan metabolism is increasingly recognized as a critical hub connecting gut, immune, brain, and metabolic health. Gut bacteria transform tryptophan into a range of indole metabolites, including IPA – a metabolite that supports gut barrier integrity, modulates immune responses, and helps protect against oxidative stress.

Emerging research shows that higher IPA levels are linked to metabolic flexibility, glucose regulation, and immune function. Conversely, when tryptophan metabolism is dysregulated, more of it is diverted into the kynurenine pathway – a route often triggered by your body’s stress responses.

By decoding your tryptophan metabolism profile, this test reveals how your gut bacteria influence immune and metabolic pathways — empowering you to make evidence-based changes to support long-term health from the inside out.

Certified & Secure Testing

• Independent laboratory: Analyzed by Vitas, a GMP-certified lab with 25+ years of experience in high-quality chromatographic analysis.
• Anonymous results: Your sample is linked only to your unique test ID; neither Zinzino nor the lab can identify you.
• Certified kit: Complies with EU regulation 98/79/EB for in vitro diagnostic medical devices and carries the CE mark.

Taking Your Test

1. For optimal accuracy: Perform this test on an empty stomach. Take it in the morning after an overnight fast of at least 10 hours before eating. Only water is permitted during the fasting period.
2. Prepare the sample: Wash your hands with warm water and soap, rinse well and dry. Take out the sample card from the paper envelope and tear off the SAVE part. Take a photo of your Test ID — this ID is required to view your results.
3. Stimulate blood flow: Make big circles with your arm or shake your hand downward for 20 seconds.
4. Collect the sample: Use the single-use lancet to prick your fingertip. Let a drop of blood fall into each circle on the card. Do not touch the filter paper with your fingers. Allow to dry for at least 10 minutes at room temperature.
5. Pack and send: Insert the sample card back into the paper envelope, place it into the metal bag, and close it. Do not remove the desiccant packet. Place the metal bag into the large return envelope with the lab address and add correct postage.
6. Register your test: Go to www.zinzinotest.com and register your test code. Results will be ready within 10–20 days.
7. Keep your SAVE part: You can only access your results with your anonymous Test ID.

Documents & Certificates

📄 Product sheet for Gut Health Test

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